Department Faculty and Their Research

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Jonathan Beckwith, Ph.D., Professor

Bacterial genetics: protein folding, protein secretion, protein disulfide bond formation and reduction, cytoplasmic redox pathways.

Thomas Livingston Benjamin, Ph.D. , Professor

Experimental cancer research using the polyoma virus-mouse system

Christophe Benoist, M.D., Ph.D. , Professor

Division of Immunology

Thomas G. Bernhardt, Ph.D., Associate Professor

Bacterial genetics; mechanism of cell division and its spatial and temporal regulation; cell wall construction

Roderick Bronson, D.V.M., Professor

Mouse pathologist studying all aspects of experimental murine disease - autoimmune, infectious, degenerative, developmental and neoplastic.

Harvey Cantor, M.D., Professor

Division of Immunology

John Collier, Ph.D., Professor

Protein structure and function; bacterial exotoxins; protein-membrane interactions.

George Th. Diamandopoulos, M.D., Professor, Emeritus

Min Dong, Ph.D., Assistant Professor

Bacterial toxins, synaptic vesicle exocytosis/trafficking, cytoskeleton remodeling, neurodegenerative diseases

Martin E. Dorf, Ph.D., Professor

Use of proteomics to investigate signaling mechanisms controlling innate antiviral immunity; Role of polyubiquitination in signalosome assembly

Dan Fraenkel, Ph.D., Senior Lecturer

Microbial metabolism, yeast glycolysis.

Michaela Gack, Ph.D., Assistant Professor

Interferon-mediated innate immune responses against viral infections and the molecular mechanisms by which viruses counteract the host anti-viral innate immunity.

Lee Gehrke, Ph.D., Professor

Regulation of gene expression through RNA-protein interactions and translation-level control mechanisms.

Michael Goldberg, Ph.D., Assistant Professor

Development and delivery of novel therapeutics to address cancer.

Darren Higgins, Ph.D., Professor

Host-pathogen interactions: intracellular bacterial pathogens; mechanisms of virulence and the host immune response.

Ann Hochschild, Ph.D., Professor

Bacterial transcription and its regulation; genetic approaches for studying protein-protein interactions.

Peter Howley, M.D., Professor

Molecular biology of the papillomaviruses; virus/host cell interactions; the role of ubiquitin ligases in human disease.

Deborah Hung, M.D., Ph.D., Associate Professor

Chemical biology, bacterial genetics and genomics; regulation of virulence, latency and drug tolerance.

Dennis Kasper, M.D., Professor

Biology of bacterial polysaccharides including immunology, virulence, structure, and use as vaccines and immunomodulators.

Elliott Kieff, M.D., Ph.D., Professor

Virology: molecular biology of Epstein-Barr virus infection and growth transformation of B lymphocytes.

David Knipe, Ph.D., Higgins Professor

Virology: molecular biology of herpes simplex virus productive and latent infection; innate immune responses to viruses; viral vaccines.

Roberto Kolter, Ph.D., Professor

Microbial molecular genetics: bacterial biofilms, interspecies interactions, genome evolution.

Stephen Lory, Ph.D., Professor

Bacterial pathogenesis: global gene regulation during host-pathogen interactions, genomics, mechanisms of secretion of bacterial virulence factors.

Diane Mathis, Ph.D. , Professor

Division of Immunology

John Mekalanos, Ph.D., Professor, Department Chair

Protein chemistry and bacterial genetics; biochemistry of bacterial toxins; genetic analysis of bacterial virulence.

Max Nibert, M.D., Ph.D., Professor

Virology: reoviruses and rotaviruses; structure and assembly, entry, transcription and RNA processing, interactions with cells, pathogenesis.

Carl D. Novina, M.D., Ph.D., Associate Professor

Fundamental biology of non-coding RNAs and their dysregulation in cancers.

David Rudner, Ph.D., Associate Professor

Spore formation in B. subtilis. Cell-cell signaling, determinants of subcellular protein localization, chromosomal organization and segregation.

Arlene Sharpe, M.D., Ph.D., Professor

Division of Immunology

Joseph G. Sodroski, M.D., Professor

Virology: human immunodeficiency virus entry into host cells; HIV pathogenesis; host restriction factors (TRIM5); HIV entry inhibitors and neutralizing antibodies.

Michael Starnbach, Ph.D., Professor

T-lymphocyte responses to bacterial pathogens; subcellular compartmentalization of bacterial antigens.

Shannon Turley, Ph.D., Associate Professor

Division of Immunology

Ulrich von Andrian, M.D., Ph.D., Professor

Division of Immunology

Bruce Walker, M.D.

Mechanisms of immune control in HIV infection

Suzanne Walker, Ph.D., Professor

Chemical biology applied to microbial systems; antibiotic mechanisms; enzyme structure, function, inhibition, and engineering.

Frederick Wang, M.D., Professor

Molecular biology, pathogenesis, and therapy of Epstein-Barr virus infection and associated malignancies

Sean Whelan, Ph.D., Professor

Molecular biology of the non-segmented negative-sense (NNS) RNA viruses.

Florian Winau, M.D., Assistant Professor

Antigen presentation including saposins, NKT cell activation and hepatic stellate cells.

Priscilla L. Yang, Ph.D., Associate Professor

Chemistry and biology of host-virus interactions.

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